Genetic Damage in Human Spermatozoa

There are several types of damage that can be found in the male gamete. This book covers the genetic damage in spermatozoa that can originate during spermatogenesis, or during transit in both male and female genital tracts.

Genetic Damage in Human Spermatozoa

There are several types of damage that can be found in the male gamete. This book covers the genetic damage in spermatozoa that can originate during spermatogenesis, or during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. The purpose of this book is to provide a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.

More Books:

Genetic Damage in Human Spermatozoa
Language: en
Pages: 210
Authors: Elisabetta Baldi, Monica Muratori
Categories: Medical
Type: BOOK - Published: 2019-07-12 - Publisher: Springer

There are several types of damage that can be found in the male gamete. This book covers the genetic damage in spermatozoa that can originate during spermatogenesis, or during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well
DNA Damage in Human Spermatozoa
Language: en
Pages:
Authors: Jeremy Philip Twigg
Categories: Medical
Type: BOOK - Published: 1999 - Publisher:

Books about DNA Damage in Human Spermatozoa
A Clinician's Guide to Sperm DNA and Chromatin Damage
Language: en
Pages: 605
Authors: Armand Zini, Ashok Agarwal
Categories: Health & Fitness
Type: BOOK - Published: 2018-03-05 - Publisher: Springer

This comprehensive, up-to-date text, which brings together the key practical elements of the rapidly evolving field of sperm DNA and chromatin abnormalities, is divided thematically into five main sections. Part I discusses human sperm chromatin structure and nuclear architecture, while part II presents laboratory evaluation of sperm DNA damage, including
Mechanisms and Consequences of DNA Damage, Response and Apoptosis in Spermatozoa
Language: en
Pages:
Authors: Julian Laubenthal
Categories: Health & Fitness
Type: BOOK - Published: 2012 - Publisher:

DNA damage in spermatozoa is a crucial contributor to spontaneous abortion, severe genetic disease in the offspring and infertility. The chromatin of spermatozoa is highly compacted, transcriptionally and translationally silent, hence lacking DNA damage response (DDR). DDR foci follow within seconds after a DNA double strand break (DSB) and correlate
Sperm Chromatin
Language: en
Pages: 512
Authors: Armand Zini, Ashok Agarwal
Categories: Health & Fitness
Type: BOOK - Published: 2011-08-04 - Publisher: Springer Science & Business Media

Sperm DNA damage is common and has been associated with reduced rates of conception, impaired embryonic development and increased risk of miscarriage. Although the exact causes of sperm DNA damage are unknown, it is clear that infertile men possess substantially higher levels of sperm DNA damage than do fertile men.